Sweet syndrome-like cutaneous drug reaction

• Main Authors: Lissandra Melati da Silva (Author), Raquel de Almeida Boechat (Author), Iale Oliveira da Hora (Author), José Roberto Pereira Pegas (Author)
• Format: Book
• Published: Sociedade Brasileira de Dermatologia, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 0365-0596; 10.1590/abd1806-4841.20175367
• Keywords: Sweet syndrome; Drug eruptions; Drug hypersensitivity; Dermatology; RL1-803
• Source: Anais Brasileiros de Dermatologia, Vol 92, Iss 6, Pp 858-860 (2017)

Abstract: Cutaneous drug reactions are adverse reactions to medications that may present with different clinical features, ranging from localized to generalized lesions. In this report we describe a case of an unusual drug reaction, resembling the morphology of Sweet syndrome lesions. The patient had a psychiatric illness and was using thioridazine hydrochloride for one year. He developed infiltrated and grouped erythematous lesions on the elbows and knees three days after commencing multiple drugs (promethazine, haloperidol, mirtazapine and levomepromazine). After suspension of these four drugs and after the use of glucocorticoids, the patient had significant clinical improvement.