Astragalin improved mitochondrial function through AMPK/PGC-1α pathway and alleviated renal injury in diabetic nephropathy

• Main Authors: Yi Luo (Author), Meng-jing Wang (Author), Shu-fen Liu (Author), Shuang Yuan (Author), Hao Huang (Author)
• Format: Book
• Published: Editorial Department of Journal of Clinical Nephrology, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective To explore the effect and mechanism of astragalin （AG） in alleviating renal injury in diabetic kidney disease(DKD). Methods db/m and db/db mice aged 16 weeks were randomized into four groups of db/m, db/m+AG （5 mg/kg）, db/db and db/db+AG （5 mg/kg）. Primary Human renal cortex proximal convo...