TLRs1-10 Protein Expression in Circulating Human White Blood Cells during Bacterial and COVID-19 Infections

• Main Authors: Louise Chomel (Author), Mathieu Vogt (Author), Julien Demiselle (Author), Pierrick Le Borgne (Author), Marine Tschirhart (Author), Valentin Morandeau (Author), Hamid Merdji (Author), Laurent Miguet (Author), Julie Helms (Author), Ferhat Meziani (Author), Laurent Mauvieux (Author)
• Format: Book
• Published: Karger Publishers, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Toll-like receptors play crucial roles in the sepsis-induced systemic inflammatory response. Septic shock mortality correlates with overexpression of neutrophilic TLR2 and TLR9, while the role of TLR4 overexpression remains a debate. In addition, TLRs are involved in the pathogenesis o...