Establishment of a sensitive UPLC-MS/MS method to quantify safinamide in rat plasma

• Main Authors: Ying Wang (Author), Guan-An Zhao (Author), Xia Li (Author), En Zhang (Author), Wei Tan (Author), Jia-qi Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A fast, simple, and sensitive ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method was established for the quantification of safinamide in rat plasma. Plasma samples were treated with acetonitrile for protein precipitation, and diazepam was used as an internal standar...