Chitosan/hesperidin nanoparticles formulation: a promising approach against ethanol-induced gastric ulcers via Sirt1/FOXO1/PGC-1α/HO-1 pathway

• Main Authors: Jawaher Abdullah Alamoudi (Author), Thanaa A. El-Masry (Author), Maysa M. F. El-Nagar (Author), Enas I. El Zahaby (Author), Kadreya E. Elmorshedy (Author), Mohamed M. S. Gaballa (Author), Samar Zuhair Alshawwa (Author), Maha Alsunbul (Author), Sitah Alharthi (Author), Hanaa A. Ibrahim (Author)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Hesperidin (Hes) protects different organs from damage by acting as a potent antioxidant and anti-inflammatory. This study aims to evaluate the gastroprotective effects of free hesperidin and its chitosan nanoparticles (HNPs) against ethanol-induced gastric ulcers in rats, hypothesizing that HNPs wi...