Reactive oxygen species and sperm cells

<p>Abstract</p> <p>There is a dynamic interplay between pro- and anti-oxidant substances in human ejaculate. Excessive reactive oxygen species (ROS) generation can overwhelm protective mechanism and initiate changes in lipid and/or protein layers of sperm plasma membranes. Addition...

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Bibliographic Details
Main Authors: Kurpisz Maciej (Author), Sanocka Dorota (Author)
Format: Book
Published: BMC, 2004-03-01T00:00:00Z.
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Summary:<p>Abstract</p> <p>There is a dynamic interplay between pro- and anti-oxidant substances in human ejaculate. Excessive reactive oxygen species (ROS) generation can overwhelm protective mechanism and initiate changes in lipid and/or protein layers of sperm plasma membranes. Additionally, changes in DNA can be induced. The essential steps of lipid peroxidation have been listed as well as antioxidant substances of semen. A variety of detection techniques of lipid peroxidation have been summarized together with the lipid components of sperm membranes that can be subjected to stress. It is unsolved, a threshold for ROS levels that may induce functional sperm ability or may lead to male infertility.</p>
Item Description:10.1186/1477-7827-2-12
1477-7827