Synchronous delivery of oxygen and photosensitizer for alleviation of hypoxia tumor microenvironment and dramatically enhanced photodynamic therapy

• Main Authors: Xiaomeng Guo (Author), Jiaxin Qu (Author), Chunqi Zhu (Author), Wei Li (Author), Lihua Luo (Author), Jie Yang (Author), Xiaoyi Yin (Author), Qingpo Li (Author), Yongzhong Du (Author), Dawei Chen (Author), Yunqing Qiu (Author), Yan Lou (Author), Jian You (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Photosensitizer, proper laser irradiation, and oxygen are essential components for effective photodynamic therapy (PDT) in clinical cancer therapy. However, native hypoxic tumoral microenvironment is a major barrier hindering photodynamic reactions in vivo. Thus, we have prepared biocompatible lipos...