Simultaneous determination of human plasma protein binding of bioactive flavonoids in Polygonum orientale by equilibrium dialysis combined with UPLCâMS/MS

• Main Authors: Yong Huang (Author), Hui Chen (Author), Feng He (Author), Zhi-Rong Zhang (Author), Lin Zheng (Author), Yue Liu (Author), Yan-Yu Lan (Author), Shang-Gao Liao (Author), Yong-Jun Li (Author), Yong-Lin Wang (Author)
• Format: Book
• Published: Elsevier, 2013-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A simple and selective ultra performance liquid chromatographyâelectrospray ionization tandem mass spectrometry (UPLCâESI-MS/MS) assay was developed for the determination of the human plasma protein binding of four bioactive flavonoids (such as orientin and vitexin) in Polygonum orientale. Protein p...