Role of chemokines in regulating luteal and uterine functions in pregnant cows

Pregnancy is intricately regulated by the interactions between various bioactive substances secreted by the conceptus, uterus, and corpus luteum (CL). Interferon-τ, synthesized and secreted by the conceptus, plays a central role in the interaction mechanism of maternal recognition in cows. Chemokine...

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Main Author: Ryosuke SAKUMOTO (Author)
Format: Book
Published: The Society for Reproduction and Development, 2024-02-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Ryosuke SAKUMOTO  |e author 
245 0 0 |a Role of chemokines in regulating luteal and uterine functions in pregnant cows 
260 |b The Society for Reproduction and Development,   |c 2024-02-01T00:00:00Z. 
500 |a 0916-8818 
500 |a 1348-4400 
500 |a 10.1262/jrd.2023-100 
520 |a Pregnancy is intricately regulated by the interactions between various bioactive substances secreted by the conceptus, uterus, and corpus luteum (CL). Interferon-τ, synthesized and secreted by the conceptus, plays a central role in the interaction mechanism of maternal recognition in cows. Chemokines, chemotaxis mediators that are primarily secreted by immune cells, regulate various reproductive responses in various species. Although there are scattered reports on the potential roles of chemokines in the bovine CL and the uterus during the estrous cycle, there is little information on chemokines in these organs during pregnancy. Therefore, in this review, we discuss the possible physiological roles of chemokines in the CL and uterus of pregnant cows, focusing on our recent findings on chemokines and changes in their receptor expression in the CL and endometrium of cows at some stages of pregnancy. 
546 |a EN 
690 |a chemokines 
690 |a corpus luteum 
690 |a cow 
690 |a pregnancy 
690 |a uterus 
690 |a Reproduction 
690 |a QH471-489 
690 |a Internal medicine 
690 |a RC31-1245 
655 7 |a article  |2 local 
786 0 |n The Journal of Reproduction and Development, Vol 70, Iss 3, Pp 145-151 (2024) 
787 0 |n https://www.jstage.jst.go.jp/article/jrd/70/3/70_2023-100/_pdf/-char/en 
787 0 |n https://doaj.org/toc/0916-8818 
787 0 |n https://doaj.org/toc/1348-4400 
856 4 1 |u https://doaj.org/article/c8d34b9fa9ec4cd0bc844186581c5e6c  |z Connect to this object online.