3-Amino-5-(indol-3-yl)methylene-4-oxo-2-thioxothiazolidine Derivatives as Antimicrobial Agents: Synthesis, Computational and Biological Evaluation

• Main Authors: Volodymyr Horishny (Author), Victor Kartsev (Author), Vasyl Matiychuk (Author), Athina Geronikaki (Author), Petrou Anthi (Author), Pavel Pogodin (Author), Vladimir Poroikov (Author), Marija Ivanov (Author), Marina Kostic (Author), Marina D. Soković (Author), Phaedra Eleftheriou (Author)
• Format: Book
• Published: MDPI AG, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Herein we report the design, synthesis, computational, and experimental evaluation of the antimicrobial activity of fourteen new 3-amino-5-(indol-3-yl) methylene-4-oxo-2-thioxothiazolidine derivatives. The structures were designed, and their antimicrobial activity and toxicity were predicted in sili...