Alkaline phosphatase levels of murine pre-osteoblastic cells on anodized and annealed titanium surfaces
Purpose This study aimed to evaluate the initial adhesion morphology and alkaline phosphatase (ALP) activity of murine pre-osteoblastic MC3T3-E1 cells cultured on anatase/rutile mixed-phase TiO2 thin films with photocatalytical activity with previously confirmed antibacterial properties. Materials a...
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| Main Authors: | , |
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| Format: | Book |
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Istanbul University,
2018-01-01T00:00:00Z.
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| Summary: | Purpose This study aimed to evaluate the initial adhesion morphology and alkaline phosphatase (ALP) activity of murine pre-osteoblastic MC3T3-E1 cells cultured on anatase/rutile mixed-phase TiO2 thin films with photocatalytical activity with previously confirmed antibacterial properties. Materials and methods Anatase/rutile mixed-phase TiO2 thin films fabricated by anodization and annealing of cpTi were used to culture MC3T3-E1 cells to evaluate the initial cellular adhesion morphology and ALP activity in vitro. Results Compared with MC3T3-E1 cells cultured on cpTi substrates and the control group, cells cultured on anatase/rutile mixed-phase TiO2 thin films exhibited similar ALP levels after cell culture day 9. Conclusion Anodizing and annealing processes fabricate multifunctional surfaces on cpTi with improved osteogenic properties for implants. |
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| Item Description: | 2630-6158 2651-2823 |