Terminal Deoxynucleotidyl Transferase (TdT) Inhibiti on of Cord Blood Derived B and T Cells Expansion

• Main Authors: Sanaz Gholami (Author), Seyede Momeneh Mohammadi (Author), Aliakbar Movasaghpour Akbari (Author), Ali Abedelahi (Author), Alireza Alihemmati (Author), Shirin Fallahi (Author), Hojjatollah Nozad Charoudeh (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Terminal deoxynucleotidyl transferase(TdT) is a DNA polymerase that is present in immature pre-B and pre-T cells. TdT inserts N-nucleotides to the V (D) J gene segment during rearrangements of genes, therefore, it plays a vital role in the development and variation of the immune system in v...