Investigation on formulation parameters of donepezil HCl loaded solid lipid nanoparticles

• Main Authors: Gizem Rüya Topal (Author), Berrin Küçüktürkmen (Author), Umut Can Öz (Author), Erva Özkan (Author), Filiz Bakar-Ates (Author), Asuman Bozkır (Author)
• Format: Book
• Published: Universidade de São Paulo, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Donepezil-HCl is a member of the acetylcholinesterase inhibitors that is indicated for the symptomatic treatment of Alzheimer's disease (AD) and has many side effects. In this study, to reduce the side effects of Donepezil-HCl and increase the penetration of the drug through the blood-...