Inhibition of HSP90 Preserves Blood-Brain Barrier Integrity after Cortical Spreading Depression

• Hauptverfasser: Seph M. Palomino (Verfasst von), Aidan A. Levine (Verfasst von), Jared Wahl (Verfasst von), Erika Liktor-Busa (Verfasst von), John M. Streicher (Verfasst von), Tally M. Largent-Milnes (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2022-08-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Cortical spreading depression (CSD) is a pathophysiological mechanism underlying headache disorders, including migraine. Blood-brain barrier (BBB) permeability is increased during CSD. Recent papers have suggested that heat shock proteins (HSP) contribute to the integrity of the blood-brain barrier....