Is Ozone therapy an adjunct treatment for SARS-CoV-2 / COVID-19 infection?
Abstract Up to today, there is no specific treatment against SARS-CoV-2 / COVID-19 infection; there the necessity to search for alternatives that help patients with COVID-19. The objective of this study was to review the use of ozone therapy as adjunct treatment for SARS-CoV-2 / COVID-19 infection,...
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Universidade de São Paulo,
2022-11-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | doaj_c96d9f83127b4fcd9ccc4d2dba738a7c | ||
042 | |a dc | ||
100 | 1 | 0 | |a Pedro Iván Arias-Vázquez |e author |
700 | 1 | 0 | |a Russell Arcila-Novelo |e author |
700 | 1 | 0 | |a María Antonieta Ramírez-Wakamatzu |e author |
245 | 0 | 0 | |a Is Ozone therapy an adjunct treatment for SARS-CoV-2 / COVID-19 infection? |
260 | |b Universidade de São Paulo, |c 2022-11-01T00:00:00Z. | ||
500 | |a 2175-9790 | ||
500 | |a 10.1590/s2175-97902022e20775 | ||
520 | |a Abstract Up to today, there is no specific treatment against SARS-CoV-2 / COVID-19 infection; there the necessity to search for alternatives that help patients with COVID-19. The objective of this study was to review the use of ozone therapy as adjunct treatment for SARS-CoV-2 / COVID-19 infection, highlighting the mechanisms of action, forms of application and current clinical evidence. A systematic review was conducted in electronic databases, searching the terminology Ozone "or" Ozone therapy "and" SARS-CoV-2 or COVID-19 or Coronavirus. Results: nineteen studies were included; ten were editorials, comments, brief reports or reviews, and nine clinical studies. We found that ozone therapy could be favorable for treating patients infected with SARS-CoV-2 / COVID-19, through a direct antiviral effect, regulation of oxidative stress, immunomodulation and improvement of oxygen metabolism. Patients who were treated with ozone therapy responded favorably; therefore, ozone therapy appears to be a promising treatment for patients infected with SARS-CoV-2 / COVID-19. Its mechanism of action justifies its use as an adjuvant therapy; however, scientific evidence is based on case series and clinical trials are necessary to corroborate its effectiveness and safety. | ||
546 | |a EN | ||
690 | |a Ozone therapy | ||
690 | |a Infection | ||
690 | |a COVID-19 | ||
690 | |a Pharmacy and materia medica | ||
690 | |a RS1-441 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022) | |
787 | 0 | |n http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100754&tlng=en | |
787 | 0 | |n https://doaj.org/toc/2175-9790 | |
856 | 4 | 1 | |u https://doaj.org/article/c96d9f83127b4fcd9ccc4d2dba738a7c |z Connect to this object online. |