Foxa2 and Pdx1 cooperatively regulate postnatal maturation of pancreatic β-cells
Objective: The transcription factors (TF) Foxa2 and Pdx1 are key regulators of beta-cell (β-cell) development and function. Mutations of these TFs or their respective cis-regulatory consensus binding sites have been linked to maturity diabetes of the young (MODY), pancreas agenesis, or diabetes susc...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2017-06-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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