Sema3A secreted by sensory nerve induces bone formation under mechanical loads

• Main Authors: Hongxiang Mei (Author), Zhengzheng Li (Author), Qinyi Lv (Author), Xingjian Li (Author), Yumeng Wu (Author), Qingchen Feng (Author), Zhishen Jiang (Author), Yimei Zhou (Author), Yule Zheng (Author), Ziqi Gao (Author), Jiawei Zhou (Author), Chen Jiang (Author), Shishu Huang (Author), Juan Li (Author)
• Format: Book
• Published: Nature Publishing Group, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Bone formation and deposition are initiated by sensory nerve infiltration in adaptive bone remodeling. Here, we focused on the role of Semaphorin 3A (Sema3A), expressed by sensory nerves, in mechanical loads-induced bone formation and nerve withdrawal using orthodontic tooth movement (OTM)...