Association of Metabolic Syndrome with the Adiponectin to Homeostasis Model Assessment of Insulin Resistance Ratio

• Main Authors: Yu-Song Ding (Author), Shu-Xia Guo (Author), Ru-Lin Ma (Author), Shu-Gang Li (Author), Heng Guo (Author), Jing-Yu Zhang (Author), Mei Zhang (Author), Jia-Ming Liu (Author), Jia He (Author), Yi-zhong Yan (Author), Wen-Jie Zhang (Author), Lie-Gang Liu (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 0962-9351; 1466-1861; 10.1155/2015/607364
• Keywords: Pathology; RB1-214
• Source: Mediators of Inflammation, Vol 2015 (2015)

This study aimed at determining whether the adiponectin to HOMA-IR (A/H) ratio is associated with MetS and MetS components and comparing the diagnostic efficacy of adiponectin, HOMA-IR, and the A/H ratio in healthy, middle-aged participants. MetS was assessed in 1628 Kazakh participants (men, 768; women, 860). The associations between adiponectin, HOMA-IR, and the A/H ratio with the components of MetS and MetS were examined using logistic regression analysis and receiver operating characteristic (ROC) curves. Our results show that A/H ratio may be a better diagnostic marker for MetS than either HOMA-IR or adiponectin alone, and it may serve as an important biomarker to determine an increased risk for MetS in healthy middle-aged population.