Oxidative Stress and Lipid Dysregulation in Lipid Droplets: A Connection to Chronic Kidney Disease Revealed in Human Kidney Cells

• Main Authors: Zhen Chen (Author), Rojeet Shrestha (Author), Xiaoyue Yang (Author), Xunzhi Wu (Author), Jiaping Jia (Author), Hitoshi Chiba (Author), Shu-Ping Hui (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic kidney disease (CKD), which is defined as a condition causing the gradual loss of kidney function, shows renal lipid droplet (LD) accumulation that is associated with oxidative damage. There is a possibility that an LD abnormality in quality plays a role in CKD development. This study aimed...