Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney disease

We describe an autopsy case of a 45-year-old male diagnosed with autosomal dominant polycystic kidney disease who presented with complaints of altered sensorium. The autopsy revealed multiple tumor-like masses in the liver, which on histological examination depicted multiple large suppurative granul...

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Main Authors: Arpitha Kollabathula (Author), Vikarn Vishwajeet (Author), Kirti Gupta (Author), Suvradeep Mitra (Author), Vibhav Sharma (Author), Pallab Ray (Author), Ashish Bhalla (Author)
Format: Book
Published: University of São Paulo, 2020-01-01T00:00:00Z.
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001 doaj_c9be8d2b80e1466e93469fe0eb9c8d9d
042 |a dc 
100 1 0 |a Arpitha Kollabathula  |e author 
700 1 0 |a Vikarn Vishwajeet  |e author 
700 1 0 |a Kirti Gupta  |e author 
700 1 0 |a Suvradeep Mitra  |e author 
700 1 0 |a Vibhav Sharma  |e author 
700 1 0 |a Pallab Ray  |e author 
700 1 0 |a Ashish Bhalla  |e author 
245 0 0 |a Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney disease 
260 |b University of São Paulo,   |c 2020-01-01T00:00:00Z. 
500 |a 10.4322/acr.2019.128 
500 |a 2236-1960 
520 |a We describe an autopsy case of a 45-year-old male diagnosed with autosomal dominant polycystic kidney disease who presented with complaints of altered sensorium. The autopsy revealed multiple tumor-like masses in the liver, which on histological examination depicted multiple large suppurative granulomas with the presence of variable acid-fast coccobacilli (consistent with Brucella spp.). Interestingly, extensive amyloid deposition in multiple organs was noted. To the best of our knowledge, this is the first case of chronic brucellosis causing tumor-like abscesses in the liver accompanied by secondary systemic amyloidosis in a patient with underlying autosomal dominant polycystic kidney disease. 
546 |a EN 
690 |a Brucellosis 
690 |a Amyloidosis 
690 |a Autopsy 
690 |a Polycystic Kidney 
690 |a Autosomal Dominant 
690 |a Medicine 
690 |a R 
690 |a Internal medicine 
690 |a RC31-1245 
655 7 |a article  |2 local 
786 0 |n Autopsy and Case Reports, Vol 10, Iss 1 (2020) 
787 0 |n http://www.revistas.usp.br/autopsy/article/view/165990 
787 0 |n https://doaj.org/toc/2236-1960 
856 4 1 |u https://doaj.org/article/c9be8d2b80e1466e93469fe0eb9c8d9d  |z Connect to this object online.