A Simple System for Differentiation of Functional Intestinal Stem Cell-like Cells from Bone Marrow Mesenchymal Stem Cells

• Main Authors: Lei Ye (Author), Lei X. Sun (Author), Min H. Wu (Author), Jin Wang (Author), Xin Ding (Author), Hui Shi (Author), Sheng L. Lu (Author), Lin Wu (Author), Juan Wei (Author), Liang Li (Author), Yu F. Wang (Author)
• Format: Book
• Published: Elsevier, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Disruption of normal barrier function is a fundamental factor in the pathogenesis of inflammatory bowel disease, and intestinal stem cell (ISC) transplantation may be an optional treatment for patients. However, it is complicated and inefficient to isolate ISCs from the intestine, which hampers its...