Comparison of the effects of 8 weeks of high intensity interval training and continuous training on P-selectin expression and platelet indices in cardiovascular disease

Platelets play an important role in the etiology of cardiovascular disease. The aim of this study was tocompare the effects of 8 weeks of high intensity interval training and continuous training on P-selectinexpression and platelet indices in cardiovascular patients. Therefore, 30 CABG and PCI heart...

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Main Authors: سجاد احمدی زاد (Author), مجید ملکی (Author), نسیم نادری (Author), هیوا رحمانی (Author), اکبر نوری حبشی (Author), مرتضی سلیمیان (Author), سارا لطفیان (Author)
Format: Book
Published: Shahid Beheshti University, 2016-05-01T00:00:00Z.
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Summary:Platelets play an important role in the etiology of cardiovascular disease. The aim of this study was tocompare the effects of 8 weeks of high intensity interval training and continuous training on P-selectinexpression and platelet indices in cardiovascular patients. Therefore, 30 CABG and PCI heart patientvoluntary participated and divided into three groups (n=10): control, continuous and high-intensity intervalgroup. Anthropometric characteristics and peak oxygen consumption was recorded before starting a workout.Each session was 40 minutes. Interval session consists of warm-up, 8 reps/ four min (exercise: 2min, activerecovery: 2min, intensity: 90 /30) and cool down, but continues session includes 30 minutes of continuousexercise intensity activity with 60% of peak oxygen consumption. The control group did not have a regularactivity. Blood samples taken before and after the eight-week and their P-selectin (by flow cytometry) andplatelet indices were measured. Repeated measure ANOVA with between group factor and multiple linearregression were used for statistical analysis. The results showed that P-selectin expression changes betweenthe groups were significantly different (P=.013). Post-hoc test show that the changes between control andinterval groups were significant (P=.011). But no significant changes were observed in all platelet indices(P>0.05).It is concluded that eight weeks of exercise leads to reduction in P-selectin expression that was alsoaffected by type of activity. Based on more effects of interval training in cardiovascular patients, use ofinterval training can be suggested in their rehabilitation program.
Item Description:2676-3710
2645-4041
10.48308/joeppa.2016.98808