Molecular mechanism of Epicedium treatment for depression based on network pharmacology and molecular docking technology

• Main Authors: Yankai Dong (Author), Bo Tao (Author), Xing Xue (Author), Caixia Feng (Author), Yating Ren (Author), Hengyu Ma (Author), Junli Zhang (Author), Yufang Si (Author), Sisi Zhang (Author), Si Liu (Author), Hui Li (Author), Jiahao Zhou (Author), Ge Li (Author), Zhifei Wang (Author), Juanping Xie (Author), Zhongliang Zhu (Author)
• Format: Book
• Published: BMC, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Increasing attention has been paid to the effect of Epimedium on the nervous system, particularly anti-depression function. In the present study, we applied network pharmacology to introduce a testable hypothesis on the multi-target mechanisms of Epicedium against depression. Met...