The broader benefits of vaccines: methodologies for inclusion in economic evaluation

Background As the societal value of vaccines is increasingly recognized, there is a need to examine methodological approaches that could be used to integrate these various benefits in the economic evaluation of a vaccine.Research design and methods A literature review and two expert panel meetings e...

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Main Authors: Steven Simoens (Author), Sandy Tubeuf (Author), Nicolas Dauby (Author), Olivier Ethgen (Author), Sophie Marbaix (Author), Marjan Willaert (Author), Jeroen Luyten (Author)
Format: Book
Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
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100 1 0 |a Steven Simoens  |e author 
700 1 0 |a Sandy Tubeuf  |e author 
700 1 0 |a Nicolas Dauby  |e author 
700 1 0 |a Olivier Ethgen  |e author 
700 1 0 |a Sophie Marbaix  |e author 
700 1 0 |a Marjan Willaert  |e author 
700 1 0 |a Jeroen Luyten  |e author 
245 0 0 |a The broader benefits of vaccines: methodologies for inclusion in economic evaluation 
260 |b Taylor & Francis Group,   |c 2024-12-01T00:00:00Z. 
500 |a 10.1080/14760584.2024.2387599 
500 |a 1744-8395 
500 |a 1476-0584 
520 |a Background As the societal value of vaccines is increasingly recognized, there is a need to examine methodological approaches that could be used to integrate these various benefits in the economic evaluation of a vaccine.Research design and methods A literature review and two expert panel meetings explored methodologies to value herd immunity, health spillover effects (beyond herd immunity), impact on antimicrobial resistance, productivity, and equity implications of vaccines.Results The consideration of broader benefits of vaccines in economic evaluation is complicated and necessitates technical expertise. Whereas methodologies to account for herd immunity and work productivity are relatively well established, approaches to investigate equity implications are developing and less frequently applied. Modeling the potential impact on antimicrobial resistance not only depends on the multi-faceted causal relationship between vaccination and resistance but also on data availability.Conclusions Different methods are available to value the broad impact of vaccines, and it is important that analysts are aware of their strengths and limitations and justify their choice of method. In the future, we expect that an increasing number of economic evaluations will consider the broader benefits of vaccines as part of their base-case analysis or in sensitivity analyses. 
546 |a EN 
690 |a Antimicrobial resistance 
690 |a economic evaluation 
690 |a equity 
690 |a health spillover effects 
690 |a herd immunity 
690 |a methodology 
690 |a Internal medicine 
690 |a RC31-1245 
655 7 |a article  |2 local 
786 0 |n Expert Review of Vaccines, Vol 23, Iss 1, Pp 779-788 (2024) 
787 0 |n https://www.tandfonline.com/doi/10.1080/14760584.2024.2387599 
787 0 |n https://doaj.org/toc/1476-0584 
787 0 |n https://doaj.org/toc/1744-8395 
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