Modified translationally controlled tumor protein-derived protein transduction domain enhances nasal delivery of exendin-4 as shown with insulin

• Main Authors: Hae-Duck Bae (Author), Moonhee Kim (Author), Joohyun Lee (Author), Kyunglim Lee (Author)
• פורמט: ספר
• יצא לאור: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Protein transduction domains (PTDs) have been shown to promote the delivery of therapeutic proteins or peptides into the living cells. In a previous study, we showed that the double mutant of TCTP-PTD 13, TCTP-PTD 13M2, was more effective in the delivery of insulin than the wild-type TCTP-PTD 13. In...