VPS13A is closely associated with mitochondria and is required for efficient lysosomal degradation
Members of the VPS13 family are associated with various human diseases. In particular, the loss of function of VPS13A leads to chorea-acanthocytosis (ChAc), a rare neurodegenerative disease without available curative treatments. Autophagy has been considered a promising therapeutic target because th...
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Main Authors: | Sandra Muñoz-Braceras (Author), Alba R. Tornero-Écija (Author), Olivier Vincent (Author), Ricardo Escalante (Author) |
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Format: | Book |
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The Company of Biologists,
2019-02-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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