Therapeutic conserved elements (CE) DNA vaccine induces strong T-cell responses against highly conserved viral sequences during simian-human immunodeficiency virus infection

• Main Authors: Paul Munson (Author), Yi Liu (Author), Debra Bratt (Author), James T. Fuller (Author), Xintao Hu (Author), George N. Pavlakis (Author), Barbara K. Felber (Author), James I. Mullins (Author), Deborah Heydenburg Fuller (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

HIV-specific T-cell responses play a key role in controlling HIV infection, and therapeutic vaccines for HIV that aim to improve viral control will likely need to improve on the T-cell responses induced by infection. However, in the setting of chronic infection, an effective therapeutic vaccine must...