Strategies for Developing Sensitive and Automated LC-MS/MS Assays of a Pharmaceutical Compound and Its Metabolite from Whole Blood Matrix
When compared with biological samples in other matrices (plasma, urine, etc.) that are typically seen in bioanalytical applications, whole blood samples present unique challenges in method development, because of the viscous nature of blood and complexity of its constituents. In this article, we hav...
Saved in:
Main Authors: | Raymond N. Xu (Author), Jill Polzin (Author), Michelle Kranz (Author), Phillip Vaca (Author), Maria Metchkarova (Author), Matthew J. Rieser (Author), Tawakol A. El-Shourbagy (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2010-04-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Quantitative Determination of ABT-925 in Human Plasma by On-Line SPE and LC-MS/MS: Validation and Sample Analysis in Phase II Studies
by: Katty Wan, et al.
Published: (2010) -
Determination of asenapine in presence of its inactive metabolites in human plasma by LC-MS/MS
by: Nirav P. Patel, et al.
Published: (2018) -
Metabolic Stability and Metabolite Characterization of Capilliposide B and Capilliposide C by LC-QTRAP-MS/MS
by: Zhongzhe Cheng, et al.
Published: (2018) -
Profiling Analysis of Tryptophan Metabolites in the Urine of Patients with Parkinson's Disease Using LC-MS/MS
by: So Hyeon Chung, et al.
Published: (2023) -
An LC-MS/MS Method for Quantification of Lamotrigine and Its Main Metabolite in Dried Blood Spots
by: Daniela Milosheska, et al.
Published: (2024)