Regulatory T cells in human lymphatic filariasis: stronger functional activity in microfilaremics.

• Main Authors: Linda J Wammes (Author), Firdaus Hamid (Author), Aprilianto E Wiria (Author), Heri Wibowo (Author), Erliyani Sartono (Author), Rick M Maizels (Author), Hermelijn H Smits (Author), Taniawati Supali (Author), Maria Yazdanbakhsh (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Infection with filarial parasites is associated with T cell hyporesponsiveness, which is thought to be partly mediated by their ability to induce regulatory T cells (Tregs) during human infections. This study investigates the functional capacity of Tregs from different groups of filarial patients to...