Leishmania donovani Utilize Sialic Acids for Binding and Phagocytosis in the Macrophages through Selective Utilization of Siglecs and Impair the Innate Immune Arm.

• Principais autores: Saptarshi Roy (Autor), Chitra Mandal (Autor)
• Formato: Livro
• Publicado em: Public Library of Science (PLoS), 2016-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

BACKGROUND:Leishmania donovani, belonging to a unicellular protozoan parasite, display the differential level of linkage-specific sialic acids on their surface. Sialic acids binding immunoglobulin-like lectins (siglecs) are a class of membrane-bound receptors present in the haematopoetic cell lineag...