Ultrasound-Responsive Nanobubbles for Combined siRNA-Cerium Oxide Nanoparticle Delivery to Bone Cells

• Main Authors: Pedram Sotoudeh Bagha (Author), Elayaraja Kolanthai (Author), Fei Wei (Author), Craig J. Neal (Author), Udit Kumar (Author), Gillian Braun (Author), Melanie Coathup (Author), Sudipta Seal (Author), Mehdi Razavi (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aims to present an ultrasound-mediated nanobubble (NB)-based gene delivery system that could potentially be applied in the future to treat bone disorders such as osteoporosis. NBs are sensitive to ultrasound (US) and serve as a controlled-released carrier to deliver a mixture of Cathepsin...