Advanced small-cell ovarian carcinoma, hypercalcemic type: a challenging therapeutic entity

• Main Authors: Rafael Caparica Bitton (Author), Milena Perez Mak (Author), Tiago Kenji Takahashi (Author), Fernando Nalesso Aguiar (Author), Elias Abdo (Author), Maria Del Pilar Estevez Diz (Author)
• Format: Book
• Published: University of São Paulo, 2014-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Small-cell ovarian carcinoma (SCOC) is a rare and aggressive neoplasia, predominantly affecting young women who are frequently first diagnosed with advanced stage disease. Platinum-based chemotherapy (ChT) can provide high response rates and rapidly ameliorate symptoms in this scenario. However, pro...