HSP Roles as Biomarkers and Antigens in Bacterial and Viral Infections

Diagnosis of infectious diseases remains an important issue in medical science. Identification of biomarkers can be used to predict early infections. Recently, heat shock proteins (HSPs) have been known as the conserved compounds expressed under stress conditions in both prokaryotic and eukaryotic s...

Full description

Saved in:
Bibliographic Details
Main Authors: Alireza Milani (Author), Marzieh Basirnejad (Author), Sepideh Shahbazi (Author), Azam Bolhassani (Author)
Format: Book
Published: Pasteur Institute of Iran, 2016-01-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

MARC

LEADER 00000 am a22000003u 4500
001 doaj_cad4c7c0c416448aafd0d66d7f56fb0d
042 |a dc 
100 1 0 |a Alireza Milani  |e author 
700 1 0 |a Marzieh Basirnejad  |e author 
700 1 0 |a Sepideh Shahbazi  |e author 
700 1 0 |a Azam Bolhassani  |e author 
245 0 0 |a HSP Roles as Biomarkers and Antigens in Bacterial and Viral Infections 
260 |b Pasteur Institute of Iran,   |c 2016-01-01T00:00:00Z. 
500 |a 2345-5349 
500 |a 2345-5330 
520 |a Diagnosis of infectious diseases remains an important issue in medical science. Identification of biomarkers can be used to predict early infections. Recently, heat shock proteins (HSPs) have been known as the conserved compounds expressed under stress conditions in both prokaryotic and eukaryotic systems. These proteins act as molecular chaperones. Several studies showed the increased levels of HSPs in patients suffering from infectious diseases suggesting the role of HSPs as promising biomarkers. Also, Hsps possess significant roles in antigen presentation, the maturation of dendritic cells and the activation of lymphocytes. Thus, these proteins can be utilized to develop vaccines in bacterial and viral infections. In this mini-review, we will briefly describe the important roles of HSPs in diagnosis and immunity in bacterial and viral infections. 
546 |a EN 
690 |a heat shock protein 
690 |a infection 
690 |a biomarker 
690 |a immunity 
690 |a Pathology 
690 |a RB1-214 
655 7 |a article  |2 local 
786 0 |n Journal of Medical Microbiology and Infectious Diseases, Vol 4, Iss 1, Pp 1-7 (2016) 
787 0 |n http://jommid.pasteur.ac.ir/article-1-119-en.html 
787 0 |n https://doaj.org/toc/2345-5349 
787 0 |n https://doaj.org/toc/2345-5330 
856 4 1 |u https://doaj.org/article/cad4c7c0c416448aafd0d66d7f56fb0d  |z Connect to this object online.