Pure red cell aplasia and seronegative myasthenia gravis in association with thymoma
Pure red cell aplasia is an uncommon paraneoplastic syndrome of thymoma. Myasthenia gravis is the most common paraneoplastic syndrome associated with thymoma. We present a case of a 79-year-old Pacific Islander female who presented with profound fatigue, generalized weakness, significant unintention...
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Greater Baltimore Medical Center,
2020-05-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | doaj_caf9de5ff8dc4c1a97a556b1c7ceb71c | ||
042 | |a dc | ||
100 | 1 | 0 | |a Sun Yong Lee |e author |
700 | 1 | 0 | |a Amandeep Gill |e author |
700 | 1 | 0 | |a Syung Min Jung |e author |
245 | 0 | 0 | |a Pure red cell aplasia and seronegative myasthenia gravis in association with thymoma |
260 | |b Greater Baltimore Medical Center, |c 2020-05-01T00:00:00Z. | ||
500 | |a 2000-9666 | ||
500 | |a 10.1080/20009666.2020.1770019 | ||
520 | |a Pure red cell aplasia is an uncommon paraneoplastic syndrome of thymoma. Myasthenia gravis is the most common paraneoplastic syndrome associated with thymoma. We present a case of a 79-year-old Pacific Islander female who presented with profound fatigue, generalized weakness, significant unintentional weight loss, bilateral ptosis, and anemia. The bone marrow biopsy showed near absence of erythroid elements consistent with pure red cell aplasia. Ice-pack test was consistent with myasthenia gravis and computed tomography of the chest demonstrated a thymoma. The patient was started on immunosuppressive treatment with prednisone and cyclosporine. This case demonstrates a rare combination of paraneoplastic manifestations of thymoma: pure red cell aplasia and myasthenia gravis. | ||
546 | |a EN | ||
690 | |a pure red cell aplasia | ||
690 | |a paraneoplastic syndrome | ||
690 | |a thymoma | ||
690 | |a myasthenia gravis | ||
690 | |a ice-pack test | ||
690 | |a Internal medicine | ||
690 | |a RC31-1245 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Journal of Community Hospital Internal Medicine Perspectives, Vol 10, Iss 3, Pp 238-241 (2020) | |
787 | 0 | |n http://dx.doi.org/10.1080/20009666.2020.1770019 | |
787 | 0 | |n https://doaj.org/toc/2000-9666 | |
856 | 4 | 1 | |u https://doaj.org/article/caf9de5ff8dc4c1a97a556b1c7ceb71c |z Connect to this object online. |