Pharmacophore modeling for biological targets with high flexibility: LXRβ case study
Many biological targets are characterized by high binding pocket flexibility posing a challenge in identifying important ligand binding features. Liver X receptors (LXRs) are members of the nuclear hormone receptor super family. Although several X-ray structures for LXRβ bound ligands are available,...
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Main Authors: | Sophia Kchouk (Author), Lamees Hegazy (Author) |
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Format: | Book |
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Elsevier,
2022-09-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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