<i>Stephania tetrandra</i> and Its Active Compound Coclaurine Sensitize NSCLC Cells to Cisplatin through EFHD2 Inhibition

• Main Authors: Shu-Yu Hu (Author), Tsai-Hui Lin (Author), Chung-Yu Chen (Author), Yu-Hao He (Author), Wei-Chien Huang (Author), Ching-Yun Hsieh (Author), Ya-Huey Chen (Author), Wei-Chao Chang (Author)
• Format: Book
• Published: MDPI AG, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Adjuvant chemotherapy, particularly cisplatin, is recommended for non-small cell lung carcinoma (NSCLC) patients at high risk of recurrence. EF-hand domain-containing protein D2 (EFHD2) has been recently shown to increase cisplatin resistance and is significantly associated with recurren...