<emph>Helicobacter pylori</emph> Seropositivity and Stool Antigen in Patients With Hyperemesis Gravidarum
<p>The objective of this paper is to investigate whether <emph>Helicobacter pylori</emph> is an etiologic factor in hyperemesis gravidarum. Thirty one patients with hyperemesis gravidarum and twenty nine pregnant controls without hyperemesis gravidarum were included in this prospec...
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Hindawi Limited,
2006-01-01T00:00:00Z.
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| Summary: | <p>The objective of this paper is to investigate whether <emph>Helicobacter pylori</emph> is an etiologic factor in hyperemesis gravidarum. Thirty one patients with hyperemesis gravidarum and twenty nine pregnant controls without hyperemesis gravidarum were included in this prospective study. All pregnant women were examined both for <emph>Helicobacter pylori</emph> serum immunoglobulin G antibodies (HpIgG Ab), showing chronic infection, and <emph>Helicobacter pylori</emph> stool antigens (HpSA), showing active gastrointestinal colonization. Chi-square and Student <mml:math alttext="$t$"> <mml:mi>t</mml:mi> </mml:math> tests were used accordingly for statistical analysis. <emph>Helicobacter pylori</emph> seropositivity was <mml:math alttext="$67.7{\%}$"> <mml:mrow> <mml:mn>67.7</mml:mn><mml:mi>%</mml:mi> </mml:mrow> </mml:math> in the patients with hyperemesis gravidarum and <mml:math alttext="$79.3{\%}$"> <mml:mrow> <mml:mn>79.3</mml:mn><mml:mi>%</mml:mi> </mml:mrow> </mml:math> in the control group <mml:math alttext="($chi^{2}=1.02$, $cmathcheck{P}=.31$)"> <mml:mrow> <mml:mrow><mml:mo>(</mml:mo> <mml:mrow> <mml:msup> <mml:mi>χ</mml:mi> <mml:mn>2</mml:mn> </mml:msup> <mml:mo>=</mml:mo><mml:mn>1.02</mml:mn><mml:mo>,</mml:mo><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>.31</mml:mn> </mml:mrow> <mml:mo>)</mml:mo></mml:mrow> </mml:mrow> </mml:math>. HpSA was detected in <mml:math alttext="$22.6{\%}$"> <mml:mrow> <mml:mn>22.6</mml:mn><mml:mi>%</mml:mi> </mml:mrow> </mml:math> of patients with hyperemesis gravidarum, whereas <mml:math alttext="$6.9{\%}$"> <mml:mrow> <mml:mn>6.9</mml:mn><mml:mi>%</mml:mi> </mml:mrow> </mml:math> of patients in the control group. The difference was not statistically significant <mml:math alttext="($chi^{2}=2.89$, $cmathcheck{P}=.08$)"> <mml:mrow> <mml:mrow><mml:mo>(</mml:mo> <mml:mrow> <mml:msup> <mml:mi>χ</mml:mi> <mml:mn>2</mml:mn> </mml:msup> <mml:mo>=</mml:mo><mml:mn>2.89</mml:mn><mml:mo>,</mml:mo><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>.08</mml:mn> </mml:mrow> <mml:mo>)</mml:mo></mml:mrow> </mml:mrow> </mml:math>. In this study, no relation was found between <emph>Helicobacter pylori</emph> and hyperemesis gravidarum. The low social status of women in both groups could be one of the reasons for the high prevalence of Hp infection.</p> |
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| Item Description: | 1064-7449 |