Antimicrobial Peptide Reverses ABCB1-Mediated Chemotherapeutic Drug Resistance

• Main Authors: Xiaofang Luo (Author), Qiu-Xu Teng (Author), Jin-Yun Dong (Author), Dong-Hua Yang (Author), Meifeng Wang (Author), Wubliker Dessie (Author), Jiang-Jiang Qin (Author), Zi-Ning Lei (Author), Jing-Quan Wang (Author), Zuodong Qin (Author), Zhe-Sheng Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multidrug resistance (MDR) of tumor cells to chemotherapeutic agents is the main reason for the failure of cancer chemotherapy. Overexpression of ABCB1 transporter that actively pumps various drugs out of the cells has been considered a major contributing factor for MDR. Over the past decade, many a...