Rethinking, reducing, and refining the classical oral tyramine challenge test of monoamine oxidase (MAO) inhibitors

Abstract The oral tyramine challenge evaluates the safety of novel monoamine oxidase (MAO) inhibitors when taken with tyramine‐containing food or drinks. In its current design, it comprises an extensive series of tyramine escalation steps until a blood pressure threshold is met. Due to the high vari...

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Bibliographic Details
Main Authors: Ewoud‐Jan vanHoogdalem (Author), Karen L. Smith (Author), Jan Hartstra (Author), John Constant (Author)
Format: Book
Published: Wiley, 2023-10-01T00:00:00Z.
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