Development and in-vitro, in-vivo evaluation of Pioglitazone-loaded polymeric nanoparticles using central composite design surface response methodology

• Główni autorzy: Dinesh Kumar Sharma (Autor), Gurudutta Pattnaik (Autor), Amulyaratna Behera (Autor)
• Format: Książka
• Wydane: Elsevier, 2023-05-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Pioglitazone is a type 2 diabetes drug encapsulated in polymeric nanoparticles using solvent evaporation techniques. In this study, the drug-polymer ratio (A), stirring speed (B), and stirring time (C) were three process parameters that were optimized using a three-factor, three-level Central Compos...