A Phase I Study to Investigate the Safety, Tolerability and Pharmacokinetics of Napabucasin Combined with Sorafenib in Japanese Patients with Unresectable Hepatocellular Carcinoma
Abstract Background and Objective For patients with advanced hepatocellular carcinoma (HCC), the standard of care for many years has been sorafenib. Preliminary data have suggested that the combination of the NAD(P)H:quinone oxidoreductase 1 bioactivatable agent napabucasin plus sorafenib may improv...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Adis, Springer Healthcare,
2023-05-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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