Fatal podophyllin poisoning with multi-organ toxicity: A case report
Accidental poisoning with household products is one of the leading causes of involuntary injuries among children in low- and middle-income countries. Podophyllin poisoning is a rare and potentially fatal occurrence. The podophyllotoxin is a lipid-soluble cytotoxic compound with no antidote and its t...
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| Main Authors: | , , , , , |
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| Format: | Book |
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Wolters Kluwer Medknow Publications,
2023-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Accidental poisoning with household products is one of the leading causes of involuntary injuries among children in low- and middle-income countries. Podophyllin poisoning is a rare and potentially fatal occurrence. The podophyllotoxin is a lipid-soluble cytotoxic compound with no antidote and its toxicity includes life-threatening neurological and multisystem complications. We report a case of a 2-year-old girl with accidental podophyllin poisoning causing multi-organ dysfunction who did not survive despite timely aggressive support and explore the possibility of early use of activated charcoal and role of extra-corporeal therapies such as hemoperfusion as a life-saving measure in such situations. |
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| Item Description: | 2349-6592 2455-7099 10.4103/jpcc.jpcc_47_23 |