TNF-α Induced the Enhanced Apoptosis of Mesenchymal Stem Cells in Ankylosing Spondylitis by Overexpressing TRAIL-R2

• Main Authors: Zhenhua Liu (Author), Liangbin Gao (Author), Peng Wang (Author), Zhongyu Xie (Author), Shuizhong Cen (Author), Yuxi Li (Author), Xiaohua Wu (Author), Le Wang (Author), Hongjun Su (Author), Wen Deng (Author), Shan Wang (Author), Deng Li (Author), Jinteng Li (Author), Yi Ouyang (Author), Yanfeng Wu (Author), Huiyong Shen (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ankylosing spondylitis (AS) is an autoimmune disease with unknown etiology. Dysregulated mesenchymal stem cells (MSCs) apoptosis may contribute to the pathogenesis of autoimmune diseases. However, apoptosis of MSCs from patients with AS (ASMSCs) has not been investigated yet. The present study aims...