Aptamer-iRNAs as Therapeutics for Cancer Treatment

Aptamers are single-stranded oligonucleotides (ssDNA or ssRNA) that bind and recognize their targets with high affinity and specificity due to their complex tertiary structure. Aptamers are selected by a method called SELEX (Systematic Evolution of Ligands by EXponential enrichment). This method has...

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Bibliographic Details
Main Authors: Mario M. Soldevilla (Author), Daniel Meraviglia-Crivelli de Caso (Author), Ashwathi P. Menon (Author), Fernando Pastor (Author)
Format: Book
Published: MDPI AG, 2018-10-01T00:00:00Z.
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