Pass and Swiss ADME collaborated in silico docking approach to the synthesis of certain pyrazoline spacer compounds for dihydrofolate reductase inhibition and antimalarial activity
New series of pyrazoline spacer compounds were prepared by the reaction between benzimidazole chalcones and (2-methyl-5-nitro-imidazole-1-yl)-acetic acid hydrazide by the sensible use of Michael addition. The building blocks used for the synthesis of pyrazoline derivatives were opted by using virtua...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Bangladesh Pharmacological Society,
2018-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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