Psoriasis/Psoriatic Arthritis Patients' Long-term Treatment Patterns and Adherence to Systemic Treatments Monitoring Recommendations

Limited information exists regarding treatment of patients with psoriasis/psoriatic arthritis in primary care. The aim of this study is to assess treatment patterns, adherence, persistence, and compliance in newly diagnosed patients with psoriasis/psoriatic arthritis from 2012 to 2018 in Stockholm,...

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Main Authors: Åsa Krantz (Author), Juan Jesus Carrero (Author), Yuanhang Yang (Author), Lovisa Schalin (Author), Josefin Lysell (Author), Faizan Mazhar (Author)
Format: Book
Published: Medical Journals Sweden, 2023-06-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Åsa Krantz  |e author 
700 1 0 |a Juan Jesus Carrero  |e author 
700 1 0 |a Yuanhang Yang  |e author 
700 1 0 |a Lovisa Schalin  |e author 
700 1 0 |a Josefin Lysell  |e author 
700 1 0 |a Faizan Mazhar  |e author 
245 0 0 |a Psoriasis/Psoriatic Arthritis Patients' Long-term Treatment Patterns and Adherence to Systemic Treatments Monitoring Recommendations 
260 |b Medical Journals Sweden,   |c 2023-06-01T00:00:00Z. 
500 |a 10.2340/actadv.v103.6505 
500 |a 0001-5555 
500 |a 1651-2057 
520 |a Limited information exists regarding treatment of patients with psoriasis/psoriatic arthritis in primary care. The aim of this study is to assess treatment patterns, adherence, persistence, and compliance in newly diagnosed patients with psoriasis/psoriatic arthritis from 2012 to 2018 in Stockholm, Sweden. In addition, laboratory monitoring before initiation of treatment and at recommended intervals was quantified for patients prescribed methotrexate or biologics. A total of 51,639 individuals were included, with 39% initiating treatment with topical corticosteroids and < 5% receiving systemic treatment within 6 months post-diagnosis. During a median (interquartile range) follow-up of 7 (4-8) years, 18% of patients received systemic treatments at some point. Overall, 5-year persistence rates were 32%, 45% and 19% for methotrexate, biologics, and other systemic treatments, respectively. Pre-initiation laboratory tests, as recommended by guidelines, were performed in approximately 70% and 62% of methotrexate and biologics users, respectively. Follow-up monitoring at recommended time intervals occurred in 14-20% and 31-33% of patients prescribed methotrexate and biologics, respectively. These findings highlight gaps in the pharmacological care of patients with psoriasis/psoriatic arthritis, including suboptimal adherence/persistence and inadequate laboratory monitoring. 
546 |a EN 
690 |a guideline concordance 
690 |a monitoring 
690 |a treatment patterns 
690 |a Adherence 
690 |a persistence 
690 |a psoriasis 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Acta Dermato-Venereologica, Vol 103 (2023) 
787 0 |n https://medicaljournalssweden.se/actadv/article/view/6505 
787 0 |n https://doaj.org/toc/0001-5555 
787 0 |n https://doaj.org/toc/1651-2057 
856 4 1 |u https://doaj.org/article/cc4ca1b427454d24b4502a1c7fcf24e6  |z Connect to this object online.