Psoriasis/Psoriatic Arthritis Patients' Long-term Treatment Patterns and Adherence to Systemic Treatments Monitoring Recommendations
Limited information exists regarding treatment of patients with psoriasis/psoriatic arthritis in primary care. The aim of this study is to assess treatment patterns, adherence, persistence, and compliance in newly diagnosed patients with psoriasis/psoriatic arthritis from 2012 to 2018 in Stockholm,...
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Medical Journals Sweden,
2023-06-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | doaj_cc4ca1b427454d24b4502a1c7fcf24e6 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Åsa Krantz |e author |
700 | 1 | 0 | |a Juan Jesus Carrero |e author |
700 | 1 | 0 | |a Yuanhang Yang |e author |
700 | 1 | 0 | |a Lovisa Schalin |e author |
700 | 1 | 0 | |a Josefin Lysell |e author |
700 | 1 | 0 | |a Faizan Mazhar |e author |
245 | 0 | 0 | |a Psoriasis/Psoriatic Arthritis Patients' Long-term Treatment Patterns and Adherence to Systemic Treatments Monitoring Recommendations |
260 | |b Medical Journals Sweden, |c 2023-06-01T00:00:00Z. | ||
500 | |a 10.2340/actadv.v103.6505 | ||
500 | |a 0001-5555 | ||
500 | |a 1651-2057 | ||
520 | |a Limited information exists regarding treatment of patients with psoriasis/psoriatic arthritis in primary care. The aim of this study is to assess treatment patterns, adherence, persistence, and compliance in newly diagnosed patients with psoriasis/psoriatic arthritis from 2012 to 2018 in Stockholm, Sweden. In addition, laboratory monitoring before initiation of treatment and at recommended intervals was quantified for patients prescribed methotrexate or biologics. A total of 51,639 individuals were included, with 39% initiating treatment with topical corticosteroids and < 5% receiving systemic treatment within 6 months post-diagnosis. During a median (interquartile range) follow-up of 7 (4-8) years, 18% of patients received systemic treatments at some point. Overall, 5-year persistence rates were 32%, 45% and 19% for methotrexate, biologics, and other systemic treatments, respectively. Pre-initiation laboratory tests, as recommended by guidelines, were performed in approximately 70% and 62% of methotrexate and biologics users, respectively. Follow-up monitoring at recommended time intervals occurred in 14-20% and 31-33% of patients prescribed methotrexate and biologics, respectively. These findings highlight gaps in the pharmacological care of patients with psoriasis/psoriatic arthritis, including suboptimal adherence/persistence and inadequate laboratory monitoring. | ||
546 | |a EN | ||
690 | |a guideline concordance | ||
690 | |a monitoring | ||
690 | |a treatment patterns | ||
690 | |a Adherence | ||
690 | |a persistence | ||
690 | |a psoriasis | ||
690 | |a Dermatology | ||
690 | |a RL1-803 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Acta Dermato-Venereologica, Vol 103 (2023) | |
787 | 0 | |n https://medicaljournalssweden.se/actadv/article/view/6505 | |
787 | 0 | |n https://doaj.org/toc/0001-5555 | |
787 | 0 | |n https://doaj.org/toc/1651-2057 | |
856 | 4 | 1 | |u https://doaj.org/article/cc4ca1b427454d24b4502a1c7fcf24e6 |z Connect to this object online. |