A combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in European American and African American families with coronary artery disease

• Main Authors: Wilson Alexander F (Author), Ruczinski Ingo (Author), Hererra-Galeano J Enrique (Author), Mantese VJ (Author), Yanek Lisa R (Author), Sung Heejong (Author), Kim Yoonhee (Author), Mathias Rasika A (Author), Faraday Nauder (Author), Becker Lewis C (Author), Becker Diane M (Author)
• Format: Book
• Published: BMC, 2010-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The inability of aspirin (ASA) to adequately suppress platelet aggregation is associated with future risk of coronary artery disease (CAD). Heritability studies of agonist-induced platelet function phenotypes suggest that genetic var...