Lack of association of the <it>CIITA </it>-168A→G promoter SNP with myasthenia gravis and its role in autoimmunity

• Main Authors: Hammarström Lennart (Author), Pirskanen Ritva (Author), Zhao Yaofeng (Author), Ramanujam Ryan (Author)
• Format: Bog
• Udgivet: BMC, 2010-10-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The major histocompatibility complex class II transactivator (CIITA) regulates MHC class II gene expression. A promoter SNP -168A→G (rs3087456) has previously been shown to be associated with susceptibility to several immune mediated...