Echovirus Type 7 Virus-Associated Hemophagocytic Syndrome in a Neonate Successfully Treated With Intravenous Immunoglobulin Therapy: A Case Report
Virus-associated hemophagocytic syndrome (VAHS) in the neonatal period has a high mortality. Although clear diagnostic criteria and treatment methods have not been established, early diagnosis and treatment are critical. However, treatments for VAHS have potentially serious side effects, especially...
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Frontiers Media S.A.,
2019-11-01T00:00:00Z.
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|---|---|---|---|
| 001 | doaj_cc950d7152f6415d8b4ac3fa18a64dea | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Yuka Watanabe |e author |
| 700 | 1 | 0 | |a Takahiro Sugiura |e author |
| 700 | 1 | 0 | |a Mari Sugimoto |e author |
| 700 | 1 | 0 | |a Yasuko Togawa |e author |
| 700 | 1 | 0 | |a Masanori Kouwaki |e author |
| 700 | 1 | 0 | |a Norihisa Koyama |e author |
| 700 | 1 | 0 | |a Shinji Saitoh |e author |
| 245 | 0 | 0 | |a Echovirus Type 7 Virus-Associated Hemophagocytic Syndrome in a Neonate Successfully Treated With Intravenous Immunoglobulin Therapy: A Case Report |
| 260 | |b Frontiers Media S.A., |c 2019-11-01T00:00:00Z. | ||
| 500 | |a 2296-2360 | ||
| 500 | |a 10.3389/fped.2019.00469 | ||
| 520 | |a Virus-associated hemophagocytic syndrome (VAHS) in the neonatal period has a high mortality. Although clear diagnostic criteria and treatment methods have not been established, early diagnosis and treatment are critical. However, treatments for VAHS have potentially serious side effects, especially during the neonatal period. Echovirus type 7 can cause maternal infection around parturition and be vertically transmitted to the neonate and induce VAHS. Intravenous immunoglobulin (IVIG) therapy could be a first-line therapy for neonatal VAHS, so that treatments with potentially serious side effects, including cyclosporine A and etoposide, could be avoided. A case of VAHS associated with echovirus type 7 that was successfully treated with IVIG therapy is reported. | ||
| 546 | |a EN | ||
| 690 | |a hemophagocytic lymphohistiocytosis | ||
| 690 | |a newborn | ||
| 690 | |a intravenous immunoglobulin therapy | ||
| 690 | |a echovirus infections | ||
| 690 | |a vertical transmission | ||
| 690 | |a Pediatrics | ||
| 690 | |a RJ1-570 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Frontiers in Pediatrics, Vol 7 (2019) | |
| 787 | 0 | |n https://www.frontiersin.org/article/10.3389/fped.2019.00469/full | |
| 787 | 0 | |n https://doaj.org/toc/2296-2360 | |
| 856 | 4 | 1 | |u https://doaj.org/article/cc950d7152f6415d8b4ac3fa18a64dea |z Connect to this object online. |