Conformational Response of 30S-bound IF3 to A-Site Binders Streptomycin and Kanamycin
Aminoglycoside antibiotics are widely used to treat infectious diseases. Among them, streptomycin and kanamycin (and derivatives) are of importance to battle multidrug-resistant (MDR) Mycobacterium tuberculosis. Both drugs bind the small ribosomal subunit (30S) and inhibit protein synthesis. Genetic...
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| Main Authors: | , , , , |
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| Format: | Book |
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MDPI AG,
2016-12-01T00:00:00Z.
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